For Dr. Gabriella Mondini, there is no other option besides following in her father’s footsteps into a life of medicine in Regina O’Melveny’s debut, The Book of Madness and Cures.  She is passionate about healing the citizens of Venice. For a woman residing in this part of the word in the late 16th Century this proves to be a challenging feat.  In the male dominated Italian medical society, Gabriella gains credibility with her father’s colleagues by assisting him with research on “The Book of Diseases.”

A few years prior, Gabriella’s father, the elder Dr. Mondini, disappeared unexpectedly with only an occasional letter as to his whereabouts.  In addition to the sporadic correspondence, his writings are cryptic and give little clue to Gabriella and her mother of his condition, which has a tendency to gravitate toward madness.  With the prospect of continuing her medical career in jeopardy without her father’s guidance, Gabriella, her maid and a few additional servants embark on a journey to solve the mystery of what happened to her father.  The journey takes them across Europe to France, Germany, England, Spain and south to the tip of Morocco, all the while encountering danger while traveling and encountering locals who met her father and are able to provide clues to the group of travelers.

While in Morocco, Gabriella finds out the shocking truth about her father, his nearly completed book on diseases and her own future.  O’Melveny’s debut provides a rich look at late 16th century day to day life, the logistics of cross continent travels and the lives of women during this time.